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رده سلولی
Similarly, spherical shaped ZnO-NPs in another investigation [35] were ob- tained via soft chemical solution process, and it was used for the treatment of bacteria (E. coli, S. aureus, P. aeru- ginosa, B. subtilis, and S. acidaminiphila) and cancer cells (HepG2 and MCF-7 cell lines).
A fluorescent dye dichlorodihydrofluorescein di- acetate (DCFH-DA) has been used recently to detect the intracellular ROS levels in bacteria and cancer cell lines [109, 110].
Thus, the mechanism related to the formation of ROS in bacteria and cell line was clearly examined by the measurement of ROS level using DCFH-DA [111].
Production of ROS by metal NPs in cell lines has been revealed by several studies [111-113], and referred to the inhibition of the respiratory enzymes [114].
Liu, Additive effect of zinc oxide nanoparticles and isoorientin on apoptosis in human hepatoma cell line.
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